In a medium bowl, add mayonnaise and buttermilk. Whisk until smooth.
Add hot sauce, ketchup, ranch seasoning, taco seasoning, paprika, cayenne pepper, cumin, salt, and pepper. Whisk until fully combined and creamy.*
Transfer to a jar or an airtight container. Refrigerate for at least 30 minutes before serving to let the flavors blend.
Serve over salads, in wraps, or as a dipping sauce for wings, fries, and more.
Notes
*If you prefer a thinner dressing, whisk in a little extra buttermilk, one tablespoon at a time. For a heartier dipping sauce, reduce buttermilk to ¼ cup.